Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311190 | 1.00 | GABBR2 (0.43) | GABBR2GABBR1GPR55PTGS1PTGS2 | |
| SCHEMBL9311194 | 1.00 | GABBR2 (0.43) | GABBR2GABBR1GPR55PTGS1PTGS2 | |
| SCHEMBL9307535 | 0.88 | GABBR2 (0.48) | GABBR2GABBR1GPR55PTGS1PTGS2 | |
| SCHEMBL9307527 | 0.88 | GABBR2 (0.48) | GABBR2GABBR1GPR55PTGS1PTGS2 | |
| SCHEMBL9307541 | 0.88 | GABBR2 (0.48) | GABBR2GABBR1GPR55PTGS1PTGS2 | |
| SCHEMBL9307546 | 0.88 | GABBR2 (0.48) | GABBR2GABBR1GPR55PTGS1PTGS2 | |
| SCHEMBL8333768 | 0.75 | ALDH1A1 (0.47) | GABBR2GABBR1GPR55NPSR1CA1 | |
| SCHEMBL6809576 | 0.72 | EPOR (0.55) | PTGS1PTGS2ALOX5 | |
| SCHEMBL31375211 | 0.70 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2NPSR1 | |
| SCHEMBL5712558 | 0.68 | GABBR2 (0.64) | GABBR2GABBR1GPR55PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352677-A | Antihyperlipidemic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0407200-B1 | Cinnamamide derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5294624-A | Antiartheriosclerosis | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5294643-A | Cinnamamide derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0407200-A1 | Cinnamamide derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-09 | — | — | EP | disclosed |