Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311202 | 0.75 | GABBR2 (0.43) | CA2CA1VCAM1CYP1A2NPSR1 | |
| SCHEMBL9311194 | 0.75 | GABBR2 (0.43) | CA2CA1VCAM1CYP1A2NPSR1 | |
| SCHEMBL9311190 | 0.75 | GABBR2 (0.43) | CA2CA1VCAM1CYP1A2NPSR1 | |
| SCHEMBL30626449 | 0.71 | ALDH1A1 (0.50) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL6951139 | 0.71 | ALDH1A1 (0.50) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL11083204 | 0.71 | CA2 (0.48) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL6951142 | 0.71 | ALDH1A1 (0.50) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL490407 | 0.71 | HMGCR (0.51) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL490766 | 0.70 | CA2 (0.47) | ALDH1A1GAATDP1CA2CA1 | |
| SCHEMBL11736846 | 0.70 | HPN (0.47) | ALDH1A1GAATDP1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009979-A1 | METHOD FOR TREATING NEUROPATHIC PAIN | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1999009829-A1 | METHOD FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |