Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.62 |
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | PTGFR | P43088 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743454 | 0.94 | PNMT (0.59) | PTGER4PTGER3PNMTPTGER2PTGER1 | |
| SCHEMBL22580526 | 0.83 | PTGFR (0.71) | PTGER4PTGER3PTGER2PTGER1PTGFR | |
| SCHEMBL6125008 | 0.83 | PTGFR (0.71) | PTGER4PTGER3PTGER2PTGER1PTGFR | |
| SCHEMBL13188360 | 0.83 | PTGFR (0.71) | PTGER4PTGER3PTGER2PTGER1PTGFR | |
| SCHEMBL21091379 | 0.83 | PTGFR (0.71) | PTGER4PTGER3PTGER2PTGER1PTGFR | |
| SCHEMBL29262298 | 0.81 | HSD11B1 (0.49) | PTGER4PTGER3PTGER2PTGFRCES2 | |
| SCHEMBL5735415 | 0.79 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL5735404 | 0.79 | PTGER4 (1.00) | PTGER4PTGER3PTGER2 | |
| SCHEMBL9442115 | 0.79 | PTGER4 (0.46) | PTGER4PTGER3PTGER2PTGER1PTGFR | |
| SCHEMBL6907990 | 0.78 | TBXAS1 (0.58) | FFAR4TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304658-A | Quinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5180742-A | Lipoxygenase Inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| EP-0171251-B2 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-12-23 | — | — | EP | disclosed |
| EP-0171251-B1 | QUINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0171251-A2 | Quinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-02-12 | — | — | EP | disclosed |