Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311405 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1PKMKMT2A | |
| SCHEMBL7904464 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1PKMKMT2A | |
| SCHEMBL9310483 | 0.82 | EGLN1 (0.46) | ALDH1A1EGLN1P2RX1HPGDKDM4E | |
| SCHEMBL9310492 | 0.82 | EGLN1 (0.46) | ALDH1A1EGLN1P2RX1HPGDKDM4E | |
| SCHEMBL7903545 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2AP2RX1 | |
| SCHEMBL7904468 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1PKMKMT2A | |
| SCHEMBL7904472 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1PKMKMT2A | |
| SCHEMBL7475632 | 0.76 | GLA (0.53) | ALDH1A1MAPTMEN1KMT2AKCNMA1 | |
| SCHEMBL7475644 | 0.76 | GLA (0.53) | ALDH1A1MAPTMEN1KMT2AKCNMA1 | |
| SCHEMBL7905583 | 0.73 | CFTR (0.45) | ALDH1A1EGLN1P2RX1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371079-A | Administering to inhibit replication of HIV-1 in human cells | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-06 | — | — | US | disclosed |
| US-5270464-A | Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-14 | — | — | US | disclosed |