Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311517 | 0.88 | HPGD (0.69) | HPGDPPARGPTPN1PIM1PIM2 | |
| SCHEMBL9311521 | 0.88 | HPGD (0.69) | HPGDPPARGPTPN1PIM1PIM2 | |
| SCHEMBL8203885 | 0.82 | HPGD (0.54) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL4762772 | 0.82 | HPGD (0.54) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL9311896 | 0.81 | HPGD (0.58) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL9433166 | 0.79 | HPGD (0.75) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL9326985 | 0.79 | CSNK2A2 (0.62) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL9312031 | 0.78 | HPGD (0.48) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL9430658 | 0.78 | HPGD (0.51) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8800183 | 0.78 | CYSLTR1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330999-A | Diabetes, obesity | ADIR ET COMPAGNIE (FR) | 1994-07-19 | — | — | US | disclosed |
| US-5296605-A | 2,4-thiazolidinedione compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |