Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312021 | 0.90 | HPGD (0.61) | HPGDPIM1PIM2CISD1HRH3 | |
| SCHEMBL9312600 | 0.79 | ALDH1A1 (0.43) | HPGD | |
| SCHEMBL9311529 | 0.78 | HPGD (0.53) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL8203885 | 0.77 | HPGD (0.54) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL4762772 | 0.77 | HPGD (0.54) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL2002768 | 0.76 | HPGD (0.59) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| Hydrochloric Acid SCHEMBL5169131 | 0.76 | PPARG (0.59) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 | |
| SCHEMBL9430175 | 0.75 | PPARG (0.40) | HPGDHRH3 | |
| SCHEMBL9430167 | 0.75 | PPARG (0.62) | HPGDHRH3 | |
| SCHEMBL9311896 | 0.72 | HPGD (0.58) | HPGDCSNK2A2CLK1CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330999-A | Diabetes, obesity | ADIR ET COMPAGNIE (FR) | 1994-07-19 | — | — | US | disclosed |
| US-5296605-A | 2,4-thiazolidinedione compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |