Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312180 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KMT2APLOD2HTTNPC1 | |
| SCHEMBL8996082 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KMT2ACYP4A11CYP4F2 | |
| SCHEMBL1980745 | 0.83 | RAB9A (0.67) | ALDH1A1CYP4A11NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3247901 | 0.81 | PLOD2 (0.65) | ALDH1A1KMT2APLOD2HDAC1HDAC8 | |
| SCHEMBL30965433 | 0.81 | PLOD2 (0.65) | ALDH1A1KMT2APLOD2HDAC1HDAC8 | |
| SCHEMBL7427297 | 0.81 | CYP4A11 (0.59) | ALDH1A1CYP4A11CYP4F2 | |
| Benzoic Acid SCHEMBL9312070 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2APLOD2HTTLMNA | |
| SCHEMBL9364176 | 0.80 | KMT2A (0.52) | KMT2APLOD2HDAC1HDAC8 | |
| SCHEMBL16316803 | 0.80 | KMT2A (0.57) | ALDH1A1KMT2APLOD2HTTHDAC1 | |
| SCHEMBL25279569 | 0.80 | TDP1 (0.72) | ALDH1A1KMT2AHTTHDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |