Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314210 | 0.88 | TRPV1 (0.53) | IMPDH2 | |
| SCHEMBL9313377 | 0.88 | MAPT (0.55) | NPC1RAB9A | |
| SCHEMBL9313383 | 0.88 | MAPT (0.55) | NPC1RAB9A | |
| SCHEMBL9312470 | 0.83 | TRPV1 (0.56) | — | |
| SCHEMBL9312463 | 0.83 | TRPV1 (0.56) | — | |
| SCHEMBL9312484 | 0.82 | ALDH1A1 (0.59) | NPC1RAB9AIMPDH2 | |
| SCHEMBL9312489 | 0.82 | ALDH1A1 (0.59) | NPC1RAB9AIMPDH2 | |
| SCHEMBL9313168 | 0.80 | MAPT (0.55) | NPC1RAB9A | |
| SCHEMBL9313174 | 0.80 | MAPT (0.55) | NPC1RAB9A | |
| SCHEMBL9312240 | 0.79 | TRPV1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |