Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972512 | 1.00 | CYP11B2 (0.33) | CYP11B2CYP11B1KDM1ACYP17A1CYP3A4 | |
| SCHEMBL8972505 | 1.00 | CYP11B2 (0.33) | CYP11B2CYP11B1KDM1ACYP17A1CYP3A4 | |
| SCHEMBL9312429 | 1.00 | CYP11B2 (0.33) | CYP11B2CYP11B1KDM1ACYP17A1CYP3A4 | |
| SCHEMBL8972309 | 0.88 | FFAR1 (0.32) | CYP11B2CYP11B1PGR | |
| SCHEMBL9311912 | 0.88 | FFAR1 (0.32) | CYP11B2CYP11B1PGR | |
| SCHEMBL9311904 | 0.88 | FFAR1 (0.32) | CYP11B2CYP11B1PGR | |
| SCHEMBL8972300 | 0.88 | FFAR1 (0.32) | CYP11B2CYP11B1PGR | |
| SCHEMBL8972651 | 0.85 | CYP11B1 (0.32) | CYP11B2CYP11B1KDM1ACYP17A1 | |
| SCHEMBL9313050 | 0.85 | CYP11B1 (0.32) | CYP11B2CYP11B1KDM1ACYP17A1 | |
| SCHEMBL9313045 | 0.85 | CYP11B1 (0.32) | CYP11B2CYP11B1KDM1ACYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322638-A | Halophenyl substituted dioxanes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-21 | — | — | US | disclosed |