Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 12/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TTPA | P49638 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255031 | 0.91 | PSEN1 (0.50) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9313766 | 0.90 | PSEN1 (0.45) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9428287 | 0.89 | PSEN1 (0.54) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9251381 | 0.89 | PSEN1 (0.45) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9655104 | 0.86 | PSEN1 (0.49) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9427451 | 0.86 | TTPA (0.53) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9655147 | 0.85 | PSEN1 (0.49) | PSEN1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL9313495 | 0.85 | TTPA (0.44) | PSEN1PTGS1PTGS2CYP1A2CYP3A4 | |
| SCHEMBL9427829 | 0.84 | PTGS1 (0.56) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9312863 | 0.84 | BCHE (0.50) | PSEN1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |