Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710196 | 0.85 | TSHR (0.31) | TSHR | |
| SCHEMBL3910492 | 0.83 | POLB (0.43) | ALDH1A1POLBGAANPSR1 | |
| SCHEMBL11778231 | 0.81 | POLB (0.31) | POLBGAANPSR1 | |
| SCHEMBL9312003 | 0.80 | — | — | |
| SCHEMBL19788104 | 0.80 | — | — | |
| SCHEMBL13589787 | 0.78 | TSHR (0.39) | ALDH1A1TSHRPOLBGAANPSR1 | |
| SCHEMBL4672467 | 0.78 | HCAR2 (0.40) | ALDH1A1TSHR | |
| SCHEMBL12395216 | 0.77 | CYP4F2 (0.36) | TSHR | |
| SCHEMBL17697535 | 0.77 | — | — | |
| SCHEMBL8990561 | 0.77 | ABCB11 (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371001-A | Transesterification in the presence of carboxy-esterases or carboxyamidases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| US-5254718-A | Using enzyme catalyst; simplified separation, purification | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| WO-1992015547-A1 | ESTERS OF UNSYMMETRICALLY 2-SUBSTITUTED GLYCOLIC ACID DIMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-17 | — | — | WO | disclosed |