Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5113248 | 0.75 | KDM4E (0.56) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL9360647 | 0.70 | MAPT (0.68) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL15850624 | 0.70 | MAPK1 (0.41) | LMNAMAPTTP53L3MBTL1GAA | |
| SCHEMBL31392367 | 0.70 | KDM4E (0.59) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL8483152 | 0.70 | KDM4E (0.59) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL9695466 | 0.70 | ALDH1A1 (0.46) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL9671575 | 0.69 | PDE7A (0.66) | MAPTL3MBTL1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL9879361 | 0.69 | MGAM (0.44) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9695397 | 0.69 | ALDH1A1 (0.45) | LMNAMAPTL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL9693767 | 0.69 | KDM4E (0.48) | LMNAMAPTL3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6080647-A | — | — | None | — | — | JP | disclosed |
| JP-H0680647-A | NEW QUINAZOLINE DERIVATIVE | HISAMITSU PHARMACEUT CO INC | 1994-03-22 | — | — | JP | disclosed |