Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | SI | P14410 | 5/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.44 |
| ▸ | VCP | P55072 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14133162 | 0.81 | GAA (0.66) | MGAMGAASIMGAM2VCP | |
| SCHEMBL3452326 | 0.77 | APEX1 (0.52) | VCPHSD17B10APEX1KMT2AADORA2A | |
| SCHEMBL9872406 | 0.73 | KMT2A (0.72) | GAAKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7525473 | 0.72 | MAPT (0.51) | HSD17B10APEX1KMT2AADORA2AMEN1 | |
| SCHEMBL13058937 | 0.71 | VCP (0.46) | GAAVCPHSD17B10APEX1KMT2A | |
| SCHEMBL11842364 | 0.69 | APEX1 (0.58) | GAAVCPHSD17B10APEX1KMT2A | |
| SCHEMBL9312972 | 0.69 | LMNA (0.47) | GAALMNAALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL11736441 | 0.69 | MEN1 (0.56) | GAAHSD17B10KMT2AADORA2AMEN1 | |
| SCHEMBL13127132 | 0.68 | MAPK1 (0.47) | VCPHSD17B10APEX1KMT2AMEN1 | |
| SCHEMBL15850624 | 0.68 | MAPK1 (0.41) | GAAKMT2ALMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |