Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695466 | 0.75 | ALDH1A1 (0.46) | GAASMN1; SMN2HPGDHTTMAPT | |
| Hydrochloric Acid SCHEMBL9695397 | 0.74 | ALDH1A1 (0.45) | GAASMN1; SMN2HPGDHTTMAPT | |
| SCHEMBL9377015 | 0.74 | KDM4E (0.50) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9360647 | 0.70 | MAPT (0.68) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6483534 | 0.70 | RAB9A (0.64) | SMN1; SMN2NPC1RAB9AHPGDHTT | |
| SCHEMBL10866268 | 0.70 | RAB9A (0.59) | KDM4ESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9376353 | 0.70 | NPC1 (0.57) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL15850624 | 0.70 | MAPK1 (0.41) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9693698 | 0.69 | ATP4A (0.36) | KDM4ESMN1; SMN2NPC1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL9695063 | 0.69 | NPC1 (0.56) | KDM4EGAASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0234690-B1 | SULFOXIDE DERIVATIVES AND THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0234690-A1 | Sulfoxide derivatives and their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-02 | — | — | EP | disclosed |