SCHEMBL9313017

SCHEMBL9313017

N=C(N)c1cc(O)cc(O)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
PRSS1 P07477 8/20 0.52
PRSS3 P35030 6/20 0.52
PRSS2 P07478 5/20 0.52
C1S P09871 3/20 0.52
F12 P00748 2/20 0.48
BACE1 P56817 1/20 0.47
F2 P00734 5/20 0.44
PLAU P00749 3/20 0.44
PLG P00747 3/20 0.44
KLK1 P06870 2/20 0.44
KLKB1 P03952 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
F10 P00742 1/20 0.43
F7 P08709 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20194148 0.85 PRSS1 (0.50) LMNAPRSS1PRSS3PRSS2C1S
SCHEMBL13948235 0.81 PRSS1 (0.63) LMNAPRSS1PRSS3PRSS2C1S
SCHEMBL28114179 0.78 GAA (0.42) LMNAPRSS1PRSS3PRSS2C1S
SCHEMBL9312568 0.74 PRSS1 (0.50) LMNAPRSS1PRSS3PRSS2C1S
SCHEMBL7359286 0.74 PARP1 (0.61) LMNAPRSS1PRSS3PRSS2C1S
SCHEMBL2519127 0.73 PTGS1 (0.62) LMNACA12CA1CA2CA7
SCHEMBL2517133 0.73 ALDH1A1 (0.68) LMNAF2PLAUPLGKLK1
SCHEMBL2517134 0.73 ALDH1A1 (0.68) LMNAF2PLAUPLGKLK1
Hydrochloric Acid SCHEMBL3909792 0.72 PRSS1 (0.63) PRSS1PRSS3PRSS2C1SF12
SCHEMBL6022788 0.72 PRSS1 (0.48) LMNAPRSS1PRSS3PRSS2C1S

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621527-A Antistatic wear-resistant plastic for vehicles and preparation method thereof 杨连玉 2022-06-14 CN claimed
CN-114621527-A Antistatic wear-resistant plastic for vehicles and preparation method thereof 杨连玉 2022-06-14 CN disclosed
CN-114621527-A Antistatic wear-resistant plastic for vehicles and preparation method thereof 杨连玉 2022-06-14 CN disclosed
EP-2954908-B1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO CORP (JP) 2018-08-08 EP disclosed
US-9981070-B2 Coating composition and medical device TERUMO KABUSHIKI KAISHA (JP) 2018-05-29 US disclosed
CN-107108638-A Piperidyl PyrazolopyrimidinonecGMP and application thereof 拜耳制药股份公司 2017-08-29 CN disclosed
US-5366996-A Administering hydroxamic acids ELFORD HOWARD L (US) 1994-11-22 US disclosed
US-5183828-A Ribonucleotide reductase inhibitor and free radical scavenger RIET BARTHOLOMEUS VAN T (US) 1993-02-02 US disclosed
US-4942253-A INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS RIET BARTHOLOMEUS VAN T (US) 1990-07-17 US disclosed
US-4623659-A RIBONUCLEOTIDE REDUCTASE INHIBITORS RIET BARTHOLOMEUS VAN T (US) 1986-11-18 US disclosed