SCHEMBL9313503

SCHEMBL9313503

CCc1ccc(NC(=O)CC(=O)Nc2ccc(CC)cc2CC)c(CC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.43
PKM P14618 1/20 0.43
POLB P06746 5/20 0.42
LMNA P02545 1/20 0.42
RECQL P46063 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16386159 0.85 RAB9A (0.47) KMT2AALDH1A1KDM4EPOLBLMNA
SCHEMBL11423764 0.82 SMN1; SMN2 (0.48) KMT2AMEN1ALDH1A1PKMPOLB
SCHEMBL11662824 0.82 HPGD (0.51) KMT2AMEN1ALDH1A1PKMPOLB
SCHEMBL9313406 0.82 POLB (0.56) KMT2AMEN1ALDH1A1POLBLMNA
SCHEMBL11412931 0.81 GAA (0.49) KMT2AMEN1KDM4EPKMPOLB
Oxalic Acid SCHEMBL20984710 0.79 METAP2 (0.41) KMT2AMEN1ALDH1A1KDM4ELMNA
SCHEMBL28200146 0.79 BACE1 (0.39) KMT2AMEN1ALDH1A1LMNAMETAP2
SCHEMBL11411090 0.78 POLB (0.54) KMT2AMEN1PKMPOLBLMNA
SCHEMBL29625809 0.78 P2RX7 (0.43) ALDH1A1KDM4ELMNAMETAP2MAPT
SCHEMBL1604988 0.78 P2RX7 (0.43) ALDH1A1KDM4ELMNAMETAP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5338642-A Diazo type recording material comprising two couplers wherein the novel coupler used is a bis-malonamide FUJI PHOTO FILM CO., LTD. (JP) 1994-08-16 US disclosed