Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71789 | 0.71 | MEN1 (0.59) | MAPTKDM4EMEN1KMT2ANR4A2 | |
| SCHEMBL12571591 | 0.71 | CA12 (0.66) | MAPTKDM4ETP53GAAL3MBTL1 | |
| SCHEMBL13832650 | 0.69 | GAA (0.66) | MAPTKDM4EMEN1KMT2ATSHR | |
| SCHEMBL25077805 | 0.68 | KDM4E (0.49) | MAPTKDM4EMEN1KMT2ANR4A2 | |
| SCHEMBL10568581 | 0.68 | KDM4E (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL32674134 | 0.68 | MAPT (0.59) | MAPTKDM4EMEN1KMT2ATSHR | |
| SCHEMBL69400 | 0.67 | SMN1; SMN2 (0.60) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL25078205 | 0.67 | SMN1; SMN2 (0.57) | MAPTKDM4EMEN1KMT2ATSHR | |
| SCHEMBL7223213 | 0.67 | MAPT (0.54) | MAPTKDM4EMEN1KMT2ANR4A2 | |
| SCHEMBL25077809 | 0.66 | SMN1; SMN2 (0.47) | MAPTKDM4EMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |