Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711013 | 0.84 | AR (0.37) | ARKDM4ECYP11B1MEN1JAK2 | |
| SCHEMBL2989414 | 0.84 | SLC6A4 (0.38) | ARTRPA1SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL9710713 | 0.83 | AR (0.58) | ARSLC22A12ESR1MAPTESR2 | |
| SCHEMBL2991253 | 0.80 | SLC22A12 (0.39) | ARTRPA1SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL27579557 | 0.79 | AR (0.42) | ARTRPA1SLC22A12MEN1JAK2 | |
| SCHEMBL9710755 | 0.78 | CYP11B1 (0.49) | ARKDM4ECYP11B1CYP11B2MEN1 | |
| SCHEMBL9711028 | 0.76 | F9 (0.42) | ARSLC22A12CYP11B1CYP11B2GAA | |
| SCHEMBL9313686 | 0.76 | KDM4E (0.41) | KDM4ETRPA1MEN1JAK2USP2 | |
| SCHEMBL2995303 | 0.76 | CA1 (0.39) | ARKDM4ESLC22A12CYP11B1CYP11B2 | |
| SCHEMBL9710776 | 0.75 | NR5A1 (0.44) | KDM4EMEN1ESR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |