Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312041 | 0.82 | HTR7 (0.47) | SMN1; SMN2KDM4EHTR7 | |
| SCHEMBL11667959 | 0.76 | PTGS2 (0.55) | PTGS2SMN1; SMN2KDM4ESLC2A1HTR7 | |
| SCHEMBL465879 | 0.75 | — | — | |
| SCHEMBL8564222 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2 | |
| SCHEMBL11188885 | 0.72 | — | — | |
| SCHEMBL7302477 | 0.69 | HRH4 (0.31) | — | |
| SCHEMBL8475778 | 0.69 | ALDH1A1 (0.59) | PTGS2SMN1; SMN2 | |
| SCHEMBL11684042 | 0.67 | — | — | |
| SCHEMBL11683972 | 0.64 | GAA (0.41) | SMN1; SMN2KDM4E | |
| SCHEMBL343346 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371074-A | Use of saccharin derivatives as proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-12-06 | — | — | US | claimed |