Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | BLM | P54132 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | PCNA | P12004 | 1/20 | 0.49 |
| ▸ | YWHAG | P61981 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28989826 | 0.98 | KDM4E (0.58) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL24803332 | 0.85 | PARP1 (0.44) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL24802436 | 0.85 | ESR1 (0.55) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL5094928 | 0.84 | GAA (0.53) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL10948201 | 0.81 | TSHR (0.56) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL19182429 | 0.79 | GPR35 (0.47) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL1973647 | 0.78 | CA2 (0.56) | LMNAPCNACA2BCHEACHE | |
| SCHEMBL27907765 | 0.78 | KDM4E (0.67) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL1070431 | 0.78 | KDM4E (0.67) | KDM4EHPGDHSD17B10HIF1AMAPT | |
| SCHEMBL22982989 | 0.77 | KDM4E (0.72) | KDM4EHPGDHSD17B10HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |