Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | BLM | P54132 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | APEX1 | P27695 | 2/20 | 0.67 |
| ▸ | RGS12 | O14924 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.67 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070431 | 1.00 | KDM4E (0.67) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL4023960 | 0.83 | ESR1 (0.61) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL22982989 | 0.82 | KDM4E (0.72) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL31618868 | 0.82 | KDM4E (0.72) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL10414022 | 0.82 | TRPA1 (0.60) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL7854613 | 0.82 | TRPA1 (0.60) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL5271301 | 0.82 | HDAC1 (0.53) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL19420576 | 0.82 | THRB (0.46) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL7148985 | 0.82 | CA2 (0.70) | KDM4EHSD17B10HIF1AHPGDMAPT | |
| SCHEMBL5702050 | 0.82 | GAA (0.46) | KDM4EHSD17B10HIF1AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1845728-B | Pharmaceutical compositions and method of using levodopa and carbidopa | TRANSFORM PHARMACEUTICALS INC | 2013-06-19 | — | — | CN | disclosed |