Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14669268 | 1.00 | OGA (0.41) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL9314127 | 1.00 | OGA (0.41) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL20812843 | 1.00 | OGA (0.41) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL9314136 | 1.00 | OGA (0.41) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL20193825 | 0.83 | CYP2C9 (0.33) | OGAMAPK1ALDH1A1CYP2C19CYP2C9 | |
| SCHEMBL9314303 | 0.81 | LGALS8 (0.42) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL9314298 | 0.81 | LGALS8 (0.42) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL9314309 | 0.81 | LGALS8 (0.42) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL24917518 | 0.79 | OGA (0.36) | OGAMAPK1ALDH1A1THRBCD69 | |
| SCHEMBL18978073 | 0.79 | OGA (0.42) | OGALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527042-A2 | 3-deoxy-mannosamine derivatives and process for their preparation | PHARMACIA S.p.A. (IT) | 1993-02-10 | — | — | EP | claimed |
| US-5332756-A | Angiogenesis inhibitor, antitumor | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-07-26 | — | — | US | disclosed |
| EP-0527042-A2 | 3-deoxy-mannosamine derivatives and process for their preparation | PHARMACIA S.p.A. (IT) | 1993-02-10 | — | — | EP | disclosed |