SCHEMBL20812843

SCHEMBL20812843

CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 4/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.36
▸ THRB P10828 1/20 0.36
▸ CD69 Q07108 1/20 0.36
▸ CYP2C19 P33261 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ PYGB P11216 2/20 0.34
▸ GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14669268 1.00 OGA (0.41) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL9314127 1.00 OGA (0.41) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL9314131 1.00 OGA (0.41) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL9314136 1.00 OGA (0.41) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL20193825 0.83 CYP2C9 (0.33) OGAMAPK1ALDH1A1CYP2C19CYP2C9
SCHEMBL9314303 0.81 LGALS8 (0.42) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL9314298 0.81 LGALS8 (0.42) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL9314309 0.81 LGALS8 (0.42) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL24917518 0.79 OGA (0.36) OGAMAPK1ALDH1A1THRBCD69
SCHEMBL18978073 0.79 OGA (0.42) OGALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190076539-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Theraprutics, Inc. (US) 2019-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190076539-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION GCGR, STUB1, GID4 OGA 225/4885MAPK1 4597/4885ALDH1A1 3398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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