Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.57 |
| ▸ | AGT | P01019 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610 | 0.88 | AGTR1 (0.62) | AGTR1AGTR2AGTABCC4ABCB11 | |
| SCHEMBL498022 | 0.87 | AGTR2 (0.63) | AGTR1AGTR2AGT | |
| SCHEMBL9313215 | 0.86 | AGTR2 (0.56) | AGTR1AGTR2AGTABCC4ABCB11 | |
| SCHEMBL1970340 | 0.85 | AGTR1 (0.64) | AGTR1AGTR2AGT | |
| SCHEMBL894 | 0.85 | GP6 (0.62) | AGTR1AGTR2AGTABCC4ABCB11 | |
| SCHEMBL6711100 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2AGTABCC4ABCB11 | |
| SCHEMBL7308711 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2AGT | |
| SCHEMBL13037616 | 0.84 | AGTR1 (0.62) | AGTR1AGTR2AGTABCC4ABCB11 | |
| Water SCHEMBL2576559 | 0.84 | AGTR1 (0.63) | AGTR1AGTR2AGT | |
| SCHEMBL7299364 | 0.84 | AGTR1 (0.53) | AGTR1AGTR2AGTABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298517-A | An imidazole derivative | AMERICAN CYANAMID COMPANY (US) | 1994-03-29 | — | — | US | disclosed |