Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485305 | 0.84 | HPGD (0.67) | HPGDKMT2AMEN1TDP1RAB9A | |
| SCHEMBL31339222 | 0.80 | KMT2A (0.64) | HPGDKMT2AMEN1TDP1RAB9A | |
| Hydrochloric Acid SCHEMBL9313499 | 0.79 | HPGD (0.61) | HPGDKMT2AMEN1TDP1RAB9A | |
| SCHEMBL9314355 | 0.79 | KMT2A (0.66) | HPGDKMT2AMEN1TDP1RAB9A | |
| SCHEMBL9314349 | 0.77 | KMT2A (0.64) | HPGDKMT2AMEN1TDP1RAB9A | |
| SCHEMBL1568625 | 0.76 | HDAC6 (0.57) | KMT2AEGLN1CTSB | |
| SCHEMBL10655393 | 0.75 | KDM4E (0.56) | KMT2AEGLN1TDP1CTSB | |
| SCHEMBL7572059 | 0.73 | P2RX7 (0.60) | HPGDKMT2AMEN1RAB9A | |
| SCHEMBL355357 | 0.73 | ALDH1A1 (0.59) | KMT2AEGLN1TDP1RAB9ANPC1 | |
| SCHEMBL8284968 | 0.73 | KMT2A (0.62) | HPGDKMT2AMEN1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286721-A | Antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0549600-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| EP-0506982-A1 | 1-AZABICYCLO 3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| WO-1992006978-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-30 | — | — | WO | disclosed |
| WO-1992005163-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1992-04-02 | — | — | WO | disclosed |