Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315237 | 0.85 | ALDH1A1 (0.51) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL31538762 | 0.83 | NPC1 (0.48) | KMT2ANPC1MEN1POLBALDH1A1 | |
| SCHEMBL1862852 | 0.81 | ALDH1A1 (0.61) | KMT2ANPC1MEN1POLBALDH1A1 | |
| SCHEMBL17250800 | 0.81 | ALDH1A1 (0.61) | KMT2ANPC1ALDH1A1MAPTTDP1 | |
| SCHEMBL18241562 | 0.81 | G6PD (0.61) | NPC1ALDH1A1MAPTTDP1FBP1 | |
| SCHEMBL9315878 | 0.80 | EGFR (0.42) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL6372930 | 0.80 | TSHR (0.54) | KMT2ANPC1MEN1POLBALDH1A1 | |
| SCHEMBL9316413 | 0.79 | CA1 (0.59) | NPC1POLBALDH1A1MAPTTDP1 | |
| SCHEMBL33368 | 0.77 | NPC1 (0.77) | KMT2ANPC1MEN1POLBALDH1A1 | |
| SCHEMBL9315897 | 0.76 | MAOB (0.55) | KMT2ANPC1POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5208949-A | — | — | None | — | — | JP | disclosed |
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| JP-H05208949-A | ALKALI-SOLUBLE NITRONE COMPOUND AND PHOTODECOLORING MATERIAL | SHIN ETSU CHEM CO LTD | 1993-08-20 | — | — | JP | disclosed |