SCHEMBL1862852

SCHEMBL1862852

CN(C)c1ccc(C=[N+]([O-])c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.61
MAPT P10636 8/20 0.61
ALOX15 P16050 2/20 0.61
TSHR P16473 2/20 0.61
RECQL P46063 1/20 0.61
RELA Q04206 1/20 0.53
G6PD P11413 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
LMNA P02545 4/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
JAK2 O60674 1/20 0.47
MITF O75030 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
NTSR1 P30989 1/20 0.47
CYP2C19 P33261 1/20 0.47
KDM4E B2RXH2 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19875637 0.84 ALDH1A1 (0.80) ALDH1A1MAPTALOX15TSHRRECQL
SCHEMBL506334 0.81 ALDH1A1 (0.56) ALDH1A1MAPTALOX15TSHRRECQL
SCHEMBL9314635 0.81 KMT2A (0.50) ALDH1A1MAPTALOX15TSHRRECQL
SCHEMBL12349218 0.80 ALDH1A1 (0.73) ALDH1A1MAPTALOX15TSHRRECQL
SCHEMBL264277 0.80 ALDH1A1 (0.73) ALDH1A1MAPTALOX15TSHRRECQL
SCHEMBL264278 0.80 ALDH1A1 (0.73) ALDH1A1MAPTALOX15TSHRRECQL
SCHEMBL12349220 0.80 RAB9A (0.70) ALDH1A1MAPTALOX15RELANPC1
SCHEMBL2995976 0.80 RAB9A (0.70) ALDH1A1MAPTALOX15RELANPC1
SCHEMBL11408631 0.79 ALDH1A1 (0.67) ALDH1A1MAPTALOX15TSHRRECQL
Hydrochloric Acid SCHEMBL3390220 0.79 RAB9A (0.68) ALDH1A1MAPTALOX15RELANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7935212-B2 Process for transferring onto a surface of an optical article a layer having a variable index of refraction ESSILOR INTERNATIONAL COMPAGNIE (FR) 2011-05-03 US disclosed
US-7840108-B2 Light branching optical waveguide HITACHI CHEMICAL CO., LTD. (JP) 2010-11-23 US disclosed
US-7496254-B2 Curved optical waveguide and optical device HITACHI CHEMICAL COMPANY, LTD. (JP) 2009-02-24 US disclosed
US-7457498-B2 Optical waveguide structure HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-25 US disclosed
US-7450803-B2 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-7444050-B2 S-shaped curved optical waveguide and optical device HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-10-28 US disclosed
WO-2008015210-A1 PROCESS FOR TRANSFERRING ONTO A SURFACE OF AN OPTICAL ARTICLE A LAYER HAVING A VARIABLE INDEX OF REFRACTION ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2008-02-07 WO disclosed
US-20080023137-A1 Process for Transferring onto a Surface of an Optical Article a Layer Having a Variable Index of Refraction ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2008-01-31 US disclosed
US-20070154141-A1 Curved optical waveguide and optical device HITACHI CHEMICAL CO. LTD. (JP) 2007-07-05 US disclosed
US-20070086705-A1 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-04-19 US disclosed
US-20070036486-A1 Light branching optical waveguide HITACHI CHEMICAL CO., LTD. (JP) 2007-02-15 US disclosed
US-20070036501-A1 S-shaped curved optical waveguide and optical device HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-02-15 US disclosed
US-20070031087-A1 Optical waveguide structure HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-7109053-B2 Method for preparing optical device by dicing HITACHI CHEMICAL CO., LTD. (JP) 2006-09-19 US disclosed
US-20040218883-A1 Method for preparing optical device and optical device HITACHI CHEMICAL CO., LTD. (JP) 2004-11-04 US disclosed
US-3988159-A Light-sensitive material containing nitrone for forming heat-fixed images AMERICAN CAN COMPANY (US) 1976-10-26 US disclosed