Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721919 | 1.00 | ALDH1A1 (0.33) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL327485 | 0.82 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL18540883 | 0.78 | MGLL (0.34) | KMT2A | |
| SCHEMBL8004731 | 0.76 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL9314819 | 0.76 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL10075274 | 0.76 | SMN1; SMN2 (0.35) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16133577 | 0.75 | MGLL (0.35) | ALDH1A1MEN1KMT2ALMNARAB9A | |
| SCHEMBL261924 | 0.75 | MGLL (0.35) | ALDH1A1MEN1KMT2ALMNARAB9A | |
| SCHEMBL7006081 | 0.74 | ACE (0.34) | KMT2A | |
| SCHEMBL277464 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461245-A4 | RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE | GUSTAVSON LINDA M (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0461245-A1 | RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE | NEORX CORPORATION (US) | 1991-12-18 | — | — | EP | disclosed |
| WO-1991009876-A1 | RADIOLABELED PROTEINS FOR DIAGNOSTIC OR THERAPEUTIC USE | NEORX CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |