Hydrazine

Hydrazine

SCHEMBL9314976

NN.O=C(O)c1cccc(S(=O)(=O)O)c1OS(=O)(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.41
PRSS1 P07477 3/20 0.41
PRSS2 P07478 3/20 0.41
PRSS3 P35030 3/20 0.41
ALOX15 P16050 2/20 0.40
MMP2 P08253 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MMP1 P03956 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
CASP7 P55210 2/20 0.38
CASP1 P29466 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064531 0.97 ALOX15 (0.42) F2PRSS1PRSS2PRSS3ALOX15
Ethylenediamine SCHEMBL10684380 0.92 CYP1A2 (0.39) F2PRSS1PRSS2PRSS3ALOX15
SCHEMBL9766397 0.84 ALDH1A1 (0.46) ALOX15MMP2CA1CA2MMP1
SCHEMBL11651045 0.80 MMP2 (0.50) F2PRSS1PRSS2PRSS3ALOX15
SCHEMBL7284889 0.80 F2 (0.48) F2PRSS1PRSS2PRSS3ALOX15
SCHEMBL28861367 0.77 ALDH1A1 (0.40) ALOX15MMP2CA1CA2MMP1
SCHEMBL28244595 0.77 PRNP (0.42) ALOX15MMP2CA1CA2MMP1
SCHEMBL28057527 0.77 ALB (0.50) ALOX15ALDH1A1HSD17B10MAPK1KDM4E
Hydrazine SCHEMBL9315728 0.76 HSD17B10 (0.54) F2PRSS1PRSS2PRSS3ALOX15
SCHEMBL29032363 0.74 MAPK1 (0.45) F2PRSS1PRSS2PRSS3ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286284-A Used in electrolytic coloring of aluminum RUF ERICH (DE) 1994-02-15 US disclosed
US-5202470-A Useful as stabilizing stannous compounds against oxidation, in particular in electrolytic coloring of aluminum or its alloy RUF ERICH (DE) 1993-04-13 US disclosed