SCHEMBL9315210

SCHEMBL9315210

C=CC/C(N)=C(\CC)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
FGFR4 P22455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3264414 0.84 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
SCHEMBL9315221 0.83 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
SCHEMBL18579864 0.83 ALDH1A1 (0.36) ALDH1A1TSHRFGFR4
SCHEMBL8653818 0.80 ALDH1A1 (0.32) ALDH1A1TSHRFGFR4
SCHEMBL28101040 0.77 TSHR (0.38) ALDH1A1TSHR
SCHEMBL4855321 0.76 TDP1 (0.35) ALDH1A1
SCHEMBL3357443 0.76 TDP1 (0.35) ALDH1A1
SCHEMBL11866338 0.76 ALDH1A1 (0.40) ALDH1A1TSHRFGFR4
SCHEMBL11866326 0.76 ALDH1A1 (0.40) ALDH1A1TSHRFGFR4
SCHEMBL1073423 0.75 CES2 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0285502-B1 Composite compact particles of polymer/metal, aqueous dispersions of these particles, method for their preparation and their use in biology PROLABO SA (FR) 1994-04-27 EP claimed
EP-0285502-A1 Composite compact particles of polymer/metal, aqueous dispersions of these particles, method for their preparation and their use in biology SOCIETE PROLABO (FR) 1988-10-05 EP claimed