Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500654 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL3446390 | 0.81 | LMNA (0.40) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL181586 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL29922833 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL1253039 | 0.76 | CA1 (0.54) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL10682460 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| Benzene SCHEMBL28241676 | 0.76 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL28228828 | 0.75 | LMNA (0.47) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL9315287 | 0.75 | TLR2 (0.50) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL31401930 | 0.74 | ALDH1A1 (0.73) | ALDH1A1LMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |