Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854230 | 0.85 | KMT2A (0.48) | ALDH1A1CYP3A4MAPTMEN1KMT2A | |
| SCHEMBL4865676 | 0.76 | KMT2A (0.47) | ALDH1A1MAOBMAPTRECQLMEN1 | |
| SCHEMBL7753277 | 0.75 | CYP3A4 (0.54) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL8641014 | 0.74 | KMT2A (0.35) | CYP3A4MEN1KMT2A | |
| SCHEMBL7183007 | 0.74 | CYP3A4 (0.38) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL9167461 | 0.74 | TDP1 (0.46) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL28656604 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL4267736 | 0.73 | MEN1 (0.76) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL20425429 | 0.73 | CYP3A4 (0.52) | ALDH1A1CYP3A4MAOBMAPTPOLB | |
| SCHEMBL9501468 | 0.73 | MAOB (0.55) | ALDH1A1CYP3A4MAOBMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994025505-A1 | PERFLUOROCYCLOBUTANE RING-CONTAINING POLYIMIDES | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | claimed |
| US-5364917-A | Perfluorocyclobutane ring-containing polymers | THE DOW CHEMICAL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1994025505-A1 | PERFLUOROCYCLOBUTANE RING-CONTAINING POLYIMIDES | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |