Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315348 | 1.00 | MAPT (0.56) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3900738 | 0.91 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3900730 | 0.91 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9314488 | 0.89 | LMNA (0.55) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9314491 | 0.89 | LMNA (0.55) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4883017 | 0.88 | HTR1A (0.55) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21799239 | 0.83 | PRMT1 (0.60) | MAPTLMNASMN1; SMN2NPSR1HTT | |
| SCHEMBL21799238 | 0.83 | PRMT1 (0.60) | MAPTLMNASMN1; SMN2NPSR1HTT | |
| SCHEMBL9315201 | 0.83 | HTR1A (0.47) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12151484 | 0.82 | HTR1A (0.59) | MAPTLMNASMN1; SMN2HTTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |