Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314491 | 1.00 | LMNA (0.55) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL9315348 | 0.89 | MAPT (0.56) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL9315352 | 0.89 | MAPT (0.56) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL9315374 | 0.88 | ALDH1A1 (0.44) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL3900738 | 0.87 | MAPT (0.59) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL3900730 | 0.87 | MAPT (0.59) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL9314428 | 0.83 | CTSV (0.41) | LMNAMAPTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL3904800 | 0.80 | NPC1 (0.50) | LMNAMAPTHPGDNPSR1NPC1 | |
| SCHEMBL4883017 | 0.77 | HTR1A (0.55) | LMNAMAPTHPGDNPC1RAB9A | |
| SCHEMBL15952288 | 0.76 | LMNA (0.67) | LMNAMAPTHPGDNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |