Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93165 | 0.89 | HRH3 (0.37) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL93191 | 0.78 | HRH3 (0.46) | HRH3CYP1A2MAPK1SMN1; SMN2MAPT | |
| SCHEMBL20333471 | 0.75 | HRH3 (0.52) | HRH3 | |
| SCHEMBL11922753 | 0.75 | HRH3 (0.52) | HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL5805106 | 0.74 | SIGMAR1 (0.38) | HRH3 | |
| SCHEMBL791887 | 0.73 | HRH3 (0.50) | HRH3CYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL12156673 | 0.72 | HRH3 (0.48) | HRH3 | |
| SCHEMBL13701446 | 0.72 | HRH3 (0.43) | HRH3MAPT | |
| SCHEMBL9033237 | 0.71 | GLA (0.38) | HRH3CYP1A2MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20332102 | 0.71 | SIGMAR1 (0.46) | HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426488-B1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEM IND LTD (JP) | 2016-04-20 | — | — | EP | disclosed |
| EP-2426123-B1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEM IND LTD (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-8663990-B2 | Measurement method utilizing internal standard substance | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8546586-B2 | Pyrazole-based cyanine dye containing quaternary ammonium cation | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| EP-2426488-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | Wako Pure Chemical Industries, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-2426123-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | Wako Pure Chemical Industries, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| US-20120043207-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | SLC43A1, HCN4, SLC7A5 | HRH3 197/4885CYP1A2 617/4885MAPK1 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.