Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93154 | 0.89 | HRH3 (0.43) | HRH3ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL5805106 | 0.84 | SIGMAR1 (0.38) | HRH3SIGMAR1SLC6A3SLC6A4CARM1 | |
| SCHEMBL9033237 | 0.81 | GLA (0.38) | HRH3SIGMAR1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL93222 | 0.76 | SIGMAR1 (0.41) | HRH3SIGMAR1ALDH1A1POLBMAPT | |
| SCHEMBL4617835 | 0.73 | SIGMAR1 (0.49) | HRH3SIGMAR1SLC6A3SLC6A4DRD2 | |
| SCHEMBL10501124 | 0.72 | L3MBTL1 (0.41) | HRH3SIGMAR1ALDH1A1POLBMAPT | |
| SCHEMBL792225 | 0.71 | SIGMAR1 (0.49) | HRH3SIGMAR1SLC6A3SLC6A4CYP1A2 | |
| SCHEMBL791957 | 0.71 | SIGMAR1 (0.49) | HRH3SIGMAR1SLC6A3SLC6A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL11609607 | 0.71 | SIGMAR1 (0.47) | HRH3SIGMAR1SLC6A3SLC6A4DRD2 | |
| SCHEMBL13962700 | 0.71 | SIGMAR1 (0.54) | HRH3SIGMAR1SLC6A3SLC6A4CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426488-B1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEM IND LTD (JP) | 2016-04-20 | — | — | EP | disclosed |
| EP-2426123-B1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEM IND LTD (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-8663990-B2 | Measurement method utilizing internal standard substance | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8546586-B2 | Pyrazole-based cyanine dye containing quaternary ammonium cation | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| EP-2426488-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | Wako Pure Chemical Industries, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-2426123-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | Wako Pure Chemical Industries, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| US-20120043207-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | SLC43A1, HCN4, SLC7A5 | HRH3 197/4885SIGMAR1 57/4885ALDH1A1 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.