Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315414 | 0.91 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EGAANPC1POLB | |
| SCHEMBL7598160 | 0.85 | KDM4E (0.69) | SMN1; SMN2KDM4EGAANPC1POLB | |
| SCHEMBL30531237 | 0.85 | KDM4E (0.69) | SMN1; SMN2KDM4EGAANPC1POLB | |
| SCHEMBL11470029 | 0.79 | KDM4E (0.69) | SMN1; SMN2KDM4EGAAALDH1A1HPGD | |
| SCHEMBL2301745 | 0.78 | KDM4E (0.77) | SMN1; SMN2KDM4EGAAPOLBALDH1A1 | |
| SCHEMBL4876987 | 0.77 | KDM4E (0.57) | SMN1; SMN2KDM4EGAANPC1POLB | |
| SCHEMBL31115738 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2KDM4EGAANPC1ALDH1A1 | |
| SCHEMBL9800425 | 0.74 | KDM4E (0.50) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9315436 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL4952910 | 0.73 | TSHR (0.57) | SMN1; SMN2KDM4EGAANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334576-A | Pre- and postemergence | AMERICAN CYANAMID COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0322616-A2 | Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1989-07-05 | — | — | EP | disclosed |