Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897534 | 0.89 | POLB (0.43) | MITFLMNAMAPTMAPK1KMT2A | |
| SCHEMBL9314498 | 0.87 | POLB (0.46) | LMNAKMT2APOLBHTR1AADRA1D | |
| SCHEMBL30483750 | 0.82 | POLB (0.52) | LMNAMAPTMAPK1POLBHTR1A | |
| SCHEMBL8912344 | 0.82 | POLB (0.52) | LMNAMAPTMAPK1POLBHTR1A | |
| SCHEMBL7291827 | 0.81 | POLB (0.56) | MITFLMNAMAPTMAPK1KMT2A | |
| SCHEMBL30390986 | 0.79 | L3MBTL1 (0.56) | MAPTMAPK1POLBELANEL3MBTL1 | |
| SCHEMBL1163314 | 0.79 | KDM1A (0.46) | MAPTPOLBHTR1AKDM4EELANE | |
| SCHEMBL9314504 | 0.78 | CTSV (0.48) | MITFLMNAMAPTMAPK1KMT2A | |
| SCHEMBL38660362 | 0.78 | TUBB4A (0.47) | MAPTRHEB | |
| SCHEMBL2085433 | 0.78 | TUBB4A (0.47) | MAPTRHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354870-A | Hair dyes | L'OREAL (FR) | 1994-10-11 | — | — | US | disclosed |
| US-5131911-A | Hair dyes | L'OREAL (FR) | 1992-07-21 | — | — | US | disclosed |