Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28199951 | 0.83 | ALDH1A1 (0.55) | TDP1SMN1; SMN2F2PRSS1PRSS2 | |
| SCHEMBL29098387 | 0.81 | ALDH1A1 (0.53) | TDP1SMN1; SMN2F2PRSS1PRSS2 | |
| SCHEMBL6544600 | 0.81 | BCAT1 (0.47) | TSHRSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL31386568 | 0.81 | TSHR (0.52) | TSHRTDP1DHFRSMN1; SMN2F2 | |
| SCHEMBL7607789 | 0.81 | TSHR (0.52) | TSHRTDP1DHFRSMN1; SMN2F2 | |
| SCHEMBL8827511 | 0.80 | TSHR (0.52) | TSHRTDP1DHFRSMN1; SMN2F2 | |
| SCHEMBL8889577 | 0.80 | F2 (0.47) | TSHRTDP1DHFRSMN1; SMN2F2 | |
| Potassium SCHEMBL30488660 | 0.79 | TSHR (0.50) | TSHRTDP1DHFRSMN1; SMN2F2 | |
| SCHEMBL28603284 | 0.79 | TSHR (0.50) | TSHRTDP1DHFRSMN1; SMN2F2 | |
| SCHEMBL27484632 | 0.79 | TSHR (0.50) | TSHRTDP1DHFRSMN1; SMN2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300676-A | Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0453846-A2 | Aryloxycarbonyl compounds | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |