Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.37 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.37 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.37 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315320 | 1.00 | ALOX15 (0.41) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL9314331 | 1.00 | ALOX15 (0.41) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL9315270 | 0.94 | POLM (0.43) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL9316283 | 0.91 | ALOX15 (0.39) | ALOX15 | |
| SCHEMBL5915964 | 0.83 | THRA (0.35) | KMT2AMEN1THRATHRBALDH1A1 | |
| SCHEMBL9315766 | 0.82 | NCEH1 (0.43) | — | |
| SCHEMBL10385987 | 0.79 | L3MBTL1 (0.35) | SMN1; SMN2THRATHRBTDP1 | |
| SCHEMBL482917 | 0.79 | EP300 (0.41) | KMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL9314372 | 0.78 | KMT2A (0.30) | KMT2A | |
| SCHEMBL9315260 | 0.77 | THRA (0.32) | PPARGPPARATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306600-A | Oxygen-containing titanocenes, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| US-5192642-A | Photoinitiators for addition photopolymerization, coatings | CIBA-GEIGY CORPORATION (US) | 1993-03-09 | — | — | US | disclosed |