SCHEMBL9315786

SCHEMBL9315786

O=C(F)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.64
ALDH1A1 P00352 2/20 0.64
L3MBTL1 Q9Y468 3/20 0.50
LMNA P02545 1/20 0.50
GLA P06280 1/20 0.42
PKM P14618 1/20 0.42
MAOA P21397 2/20 0.42
MAOB P27338 2/20 0.42
EZH2 Q15910 1/20 0.42
SIRT1 Q96EB6 1/20 0.41
CHRNA7 P36544 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 2/20 0.41
BCL2 P10415 1/20 0.41
MCL1 Q07820 1/20 0.41
CTSK P43235 1/20 0.40
FFAR1 O14842 1/20 0.39
CXCL12 P48061 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315856 0.90 HPGD (0.53) HPGDALDH1A1L3MBTL1LMNAMAPT
SCHEMBL689927 0.82 HPGD (0.69) HPGDALDH1A1L3MBTL1LMNAPKM
SCHEMBL3282737 0.82 HPGD (0.69) HPGDALDH1A1L3MBTL1LMNAPKM
SCHEMBL21506865 0.80 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNACES2
SCHEMBL11594355 0.80 CES2 (0.68) HPGDALDH1A1L3MBTL1LMNAMAOA
SCHEMBL16343282 0.80 HPGD (0.67) HPGDALDH1A1L3MBTL1LMNAGLA
SCHEMBL385623 0.80 ALDH1A1 (0.67) HPGDALDH1A1L3MBTL1LMNACES2
SCHEMBL13531602 0.78 HPGD (0.64) HPGDALDH1A1L3MBTL1LMNAMAOA
SCHEMBL2705977 0.78 ALDH1A1 (0.64) HPGDALDH1A1L3MBTL1LMNAGLA
SCHEMBL2978952 0.78 HPGD (0.64) HPGDALDH1A1L3MBTL1LMNASIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5326849-A Method for producing an aromatic poly (thio) ether ketone MITSUBISHI KASEI CORPORATION (JP) 1994-07-05 US claimed
US-5326849-A Method for producing an aromatic poly (thio) ether ketone MITSUBISHI KASEI CORPORATION (JP) 1994-07-05 US disclosed