Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.30 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192208 | 0.84 | P2RY6 (0.33) | P2RY2POLB | |
| SCHEMBL992472 | 0.78 | PDE3A (0.46) | POLB | |
| SCHEMBL6464825 | 0.71 | P2RY2 (0.42) | CA1CA2P2RY2PLA2G1BATG4B | |
| SCHEMBL6464823 | 0.71 | P2RY2 (0.42) | CA1CA2P2RY2PLA2G1BATG4B | |
| SCHEMBL8660992 | 0.69 | PDE3A (0.42) | POLB | |
| SCHEMBL438241 | 0.69 | SLC28A1 (0.44) | P2RY2 | |
| SCHEMBL7240457 | 0.67 | PDE4D (0.32) | POLB | |
| SCHEMBL6884819 | 0.67 | POLB (0.37) | POLB | |
| SCHEMBL30721625 | 0.67 | PLA2G1B (0.55) | P2RY2PLA2G1BATG4BPOLB | |
| SCHEMBL9315818 | 0.67 | PLA2G1B (0.51) | CA1CA2P2RY2PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521111-A4 | POLYNUCLEOTIDE CAPTURE ASSAY EMPLOYING IN VITRO AMPLIFICATION | CHIRON CORP (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0521111-A1 | POLYNUCLEOTIDE CAPTURE ASSAY EMPLOYING IN VITRO AMPLIFICATION | CHIRON CORPORATION (US) | 1993-01-07 | — | — | EP | disclosed |
| WO-1991014788-A1 | POLYNUCLEOTIDE CAPTURE ASSAY EMPLOYING IN VITRO AMPLIFICATION | CHIRON CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |