Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CDA | P32320 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315826 | 0.84 | CA1 (0.39) | POLBP2RY2 | |
| SCHEMBL992472 | 0.84 | PDE3A (0.46) | POLBLMNATHRBMTORMDM2 | |
| SCHEMBL6884819 | 0.81 | POLB (0.37) | P2RY6POLBLMNATHRBMTOR | |
| SCHEMBL7240457 | 0.81 | PDE4D (0.32) | P2RY6POLBLMNATHRBMTOR | |
| SCHEMBL29891526 | 0.79 | LMNA (0.36) | P2RY6POLBLMNATHRBMTOR | |
| SCHEMBL5190899 | 0.74 | PDE4D (0.37) | P2RY6POLBLMNATHRBMTOR | |
| SCHEMBL438241 | 0.74 | SLC28A1 (0.44) | P2RY6SLC29A1P2RY2P2RY4 | |
| SCHEMBL29891333 | 0.72 | LMNA (0.34) | POLBLMNATHRBMTORMDM2 | |
| SCHEMBL29413003 | 0.72 | LMNA (0.33) | P2RY6POLBLMNATHRBMTOR | |
| SCHEMBL29875732 | 0.71 | PNP (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812456-A2 | ß-L-N4-HYDROXYCYTOSINE DEOXYNUCLEOSIDES AND THEIR USE AS PHARMACEUTICAL AGENTS IN THE PROPHYLAXIS OR THERAPY OF VIRAL DISEASES | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006045616-A2 | β-L-N4-HYDROXYCYTOSINE DEOXYNUCLEOSIDES AND THEIR USE AS PHARMACEUTICAL AGENTS IN THE PROPHYLAXIS OR THERAPY OF VIRAL DISEASES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2006-05-04 | — | — | WO | disclosed |