Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CDA | P32320 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192208 | 0.81 | P2RY6 (0.33) | POLBABL1RIN1LMNATHRB | |
| SCHEMBL7240457 | 0.79 | PDE4D (0.32) | POLBABL1RIN1LMNATHRB | |
| SCHEMBL1409332 | 0.76 | SLC28A1 (0.42) | P2RY6P2RY14 | |
| SCHEMBL7013069 | 0.73 | PDE3A (0.41) | POLBLMNATHRBMTORMDM2 | |
| SCHEMBL6842457 | 0.72 | PDE3A (0.41) | POLBLMNATHRBMTORMDM2 | |
| SCHEMBL5190899 | 0.72 | PDE4D (0.37) | POLBLMNATHRBMTORMDM2 | |
| SCHEMBL29891526 | 0.72 | LMNA (0.36) | POLBLMNATHRBMTORMDM2 | |
| SCHEMBL29493048 | 0.71 | TYMP (0.44) | LMNA | |
| SCHEMBL30919320 | 0.70 | ADORA3 (0.35) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL29891333 | 0.70 | LMNA (0.34) | POLBLMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |