Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716180 | 0.97 | TSHR (0.50) | TSHRMAPK1KIF11NR2E1RXRA | |
| SCHEMBL29576147 | 0.97 | TSHR (0.50) | TSHRMAPK1KIF11NR2E1RXRA | |
| SCHEMBL23045013 | 0.95 | KIF11 (0.44) | TSHRMAPK1KIF11NR2E1RXRA | |
| SCHEMBL30600349 | 0.90 | KIF11 (0.44) | TSHRMAPK1KIF11NR2E1RXRA | |
| SCHEMBL8741826 | 0.89 | TSHR (0.55) | TSHRMAPK1KIF11RXRARXRB | |
| SCHEMBL3785139 | 0.87 | KIF11 (0.65) | TSHRMAPK1KIF11RXRARXRB | |
| SCHEMBL3783746 | 0.85 | KIF11 (0.54) | TSHRMAPK1KIF11RXRARXRB | |
| SCHEMBL30087058 | 0.85 | KIF11 (0.54) | TSHRMAPK1KIF11RXRARXRB | |
| Hydrazine SCHEMBL2139143 | 0.84 | RXRA (0.45) | TSHRMAPK1KIF11RXRARXRB | |
| SCHEMBL130383 | 0.84 | TSHR (0.56) | TSHRMAPK1KIF11NR2E1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354839-A | Low dielectric constant, colorless, transparent and excellent in processability and heat resistance | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-11 | — | — | US | disclosed |