Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199799 | 0.88 | ACHE (0.50) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| SCHEMBL29351047 | 0.84 | TOP2A (0.54) | ACHEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2956894 | 0.84 | TOP2A (0.54) | ACHEKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27092615 | 0.81 | ACHE (0.47) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| SCHEMBL27136670 | 0.79 | ACHE (0.53) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| SCHEMBL27074281 | 0.77 | ACHE (0.59) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| SCHEMBL29382084 | 0.75 | ACHE (1.00) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| SCHEMBL121401 | 0.75 | ACHE (1.00) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3234011 | 0.73 | ACHE (0.96) | ACHEPARP1CHEK1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4436954 | 0.73 | ACHE (0.96) | ACHEPARP1CHEK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |