Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316093 | 0.88 | ACHE (0.59) | ACHEPARP1MAPTCHEK1KDM4E | |
| SCHEMBL27092615 | 0.79 | ACHE (0.47) | ACHEPARP1MAPTCHEK1KDM4E | |
| SCHEMBL27136670 | 0.77 | ACHE (0.53) | ACHEPARP1MAPTCHEK1KDM4E | |
| SCHEMBL972999 | 0.76 | ACHE (0.78) | ACHEPARP1MAPTKIF11FEN1 | |
| SCHEMBL29642993 | 0.76 | ACHE (0.78) | ACHEPARP1MAPTKIF11FEN1 | |
| SCHEMBL30877776 | 0.71 | ACHE (0.50) | ACHEPARP1MAPTKIF11KDM4E | |
| SCHEMBL9315013 | 0.71 | GABRA1 (0.43) | ACHEPARP1MAPTKIF11CHEK1 | |
| SCHEMBL29351047 | 0.70 | TOP2A (0.54) | ACHEMAPTKIF11KDM4EALDH1A1 | |
| SCHEMBL2956894 | 0.70 | TOP2A (0.54) | ACHEMAPTKIF11KDM4EALDH1A1 | |
| SCHEMBL30866442 | 0.70 | CHEK1 (0.43) | ACHEPARP1MAPTCHEK1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | CKS2, CDK2, CDK1 | ACHE 606/4885PARP1 927/4885MAPT 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.