Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.77 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.77 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.77 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.77 |
| ▸ | GABRP | O00591 | 1/20 | 0.77 |
| ▸ | GABRD | O14764 | 1/20 | 0.77 |
| ▸ | IKBKB | O14920 | 1/20 | 0.77 |
| ▸ | AURKA | O14965 | 1/20 | 0.77 |
| ▸ | CHUK | O15111 | 1/20 | 0.77 |
| ▸ | PIM1 | P11309 | 1/20 | 0.77 |
| ▸ | TOP1 | P11387 | 1/20 | 0.77 |
| ▸ | IDO1 | P14902 | 1/20 | 0.77 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29382084 | 1.00 | ACHE (1.00) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3234011 | 0.98 | ACHE (0.96) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Water SCHEMBL2197266 | 0.98 | ACHE (0.96) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4436954 | 0.98 | ACHE (0.96) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL972999 | 0.89 | ACHE (0.78) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29642993 | 0.89 | ACHE (0.78) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Norharmane SCHEMBL9486853 | 0.87 | CHUK (1.00) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Norharmane SCHEMBL25834 | 0.87 | CHUK (1.00) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Carbazole SCHEMBL18684843 | 0.87 | CHUK (1.00) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Norharmane SCHEMBL29370219 | 0.87 | CHUK (1.00) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1883 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241533-A | Preparation method of tetrahydro-gamma-carboline | 湖北科技学院 | 2025-01-03 | — | — | CN | claimed |
| CN-117659008-A | Gamma-carboline ketone derivative and synthetic method and application thereof | 重庆文理学院 | 2024-03-08 | — | — | CN | claimed |
| CN-112979648-B | Synthesis method of gamma-carboline derivative | 江汉大学 | 2023-12-29 | — | — | CN | claimed |
| CN-116874482-A | Synthesis method of gamma-carboline ketone compound | 绍兴文理学院 | 2023-10-13 | — | — | CN | claimed |
| US-20230301170-A1 | ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-09-21 | — | — | US | claimed |
| CN-113880836-B | 1,5, 8-trisubstituted gamma-carboline derivative and preparation method and application thereof | 浙江中医药大学 | 2023-03-14 | — | — | CN | claimed |
| EP-4034119-A1 | NOVEL METHODS | Intra-Cellular Therapies, Inc. (US) | 2022-08-03 | — | — | EP | claimed |
| CN-111961052-B | Preparation method of gamma-carboline derivative | 沈阳师范大学 | 2022-06-03 | — | — | CN | claimed |
| CN-111808101-B | Application of gamma-carboline hydroxamic acid anti-tumor metastasis compound and preparation method thereof | 济南大学 | 2022-05-24 | — | — | CN | claimed |
| CN-112979648-A | Synthesis method of gamma-carboline derivative | 江汉大学 | 2021-06-18 | — | — | CN | claimed |
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | claimed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | claimed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | claimed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | claimed |
| EP-0392663-A1 | Carboline derivative as a 5-HT3 receptor antagonist | ONO PHARMACEUTICAL CO., LTD. (JP) | 1990-10-17 | — | — | EP | claimed |
| EP-0222474-B1 | GAMMA-CARBOLINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-03 | — | — | EP | claimed |
| EP-0223344-B1 | GAMMA-CARBOLINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-08-22 | — | — | EP | claimed |
| EP-0223344-A1 | Gamma-carbolines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-27 | — | — | EP | claimed |
| EP-0222474-A1 | Gamma-carbolines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-20 | — | — | EP | claimed |
| EP-0094774-A2 | Carboline derivatives | PFIZER INC. (US) | 1983-11-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230301170-A1 | ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE | LAGE3, GPX1, LEF1 | ACHE 225/4885ALDH1A1 30/4885KDM4E 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.