Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316443 | 1.00 | PIM1 (0.44) | PIM1PIM2PIM3HPGDPPARG | |
| SCHEMBL9316520 | 0.94 | PIM1 (0.45) | PIM1PIM2PIM3HPGDPPARG | |
| SCHEMBL9370030 | 0.94 | PIM1 (0.45) | PIM1PIM2PIM3HPGDPPARG | |
| SCHEMBL9316762 | 0.89 | HPGD (0.48) | PIM1PIM2PIM3HPGDPIK3CG | |
| SCHEMBL9316768 | 0.89 | HPGD (0.48) | PIM1PIM2PIM3HPGDPIK3CG | |
| SCHEMBL10364994 | 0.83 | HPGD (0.61) | PIM1PIM2HPGDPPARGPPARA | |
| SCHEMBL10364971 | 0.83 | HPGD (0.61) | PIM1PIM2HPGDPPARGPPARA | |
| SCHEMBL10366704 | 0.83 | HPGD (0.61) | PIM1PIM2HPGDPPARGPPARA | |
| SCHEMBL9317355 | 0.82 | PPARG (0.49) | HPGDPPARGPPARAPPARDHRH3 | |
| SCHEMBL8133136 | 0.81 | PPARG (0.57) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330998-A | Anticholesterol agents | PFIZER INC. (US) | 1994-07-19 | — | — | US | disclosed |