Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966515 | 0.83 | MGLL (0.41) | MGLLALDH1A1GLATDP1NPC1 | |
| SCHEMBL10968284 | 0.79 | ABCB1 (0.51) | MGLLALDH1A1GLATDP1ABCB1 | |
| SCHEMBL10970369 | 0.78 | ALDH1A1 (0.46) | MGLLALDH1A1GLATDP1ABCB1 | |
| SCHEMBL9808448 | 0.78 | S1PR1 (0.43) | ALDH1A1NPC1RAB9AABCB1 | |
| Hydrochloric Acid SCHEMBL10565203 | 0.77 | S1PR1 (0.42) | ALDH1A1NPC1RAB9AABCB1 | |
| SCHEMBL9808422 | 0.76 | ABCB1 (0.58) | ALDH1A1TDP1ABCB1 | |
| SCHEMBL9808491 | 0.76 | MEN1 (0.56) | ALDH1A1POLBABCB1 | |
| SCHEMBL9808381 | 0.76 | SCN1A (0.44) | ALDH1A1CYP1A2CYP3A4CYP2C19ABCB1 | |
| Hydrochloric Acid SCHEMBL9808527 | 0.76 | ABCB1 (0.57) | ALDH1A1TDP1ABCB1 | |
| SCHEMBL9808398 | 0.76 | ABCB1 (0.60) | ALDH1A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462150-B1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | LAEVOSAN GMBH & CO KG (AT) | 1994-09-07 | — | — | EP | disclosed |
| US-5334602-A | Antiarrhytmic agent | LAEVOSAN-GESELLSCHAFT GMBH (AT) | 1994-08-02 | — | — | US | disclosed |
| EP-0233173-A1 | 1-[3-(2-Hydroxy-3-alkylamino-propoxy)-2-thienyl]-3-phenyl-1-propanones and their acid addition salts, process for their preparation and pharmaceutical compositions containing them | Laevosan-Gesellschaft m.b.H. (AT) | 1987-08-19 | — | — | EP | disclosed |
| EP-0053603-B1 | 1-(3-(2-HYDROXY-3-ALKYLAMINOPROPOXY)-2-THIENYL)-3-PHENYL-1 PROPANONES AND THEIR ACID ADDITION SALTS, AND PROCESS FOR THEIR PREPARATION | Laevosan-Gesellschaft m.b.H. & Co KG (AT) | 1985-04-03 | — | — | EP | disclosed |
| US-4352819-A | ANTIARRHYTHMIA AGENTS | LAEVOSAN-GESELLSCHAFT MBH & CO. KG (AT) | 1982-10-05 | — | — | US | disclosed |
| EP-0053603-A1 | 1-(3-(2-Hydroxy-3-alkylaminopropoxy)-2-thienyl)-3-phenyl-1 propanones and their acid addition salts, and process for their preparation | Laevosan-Gesellschaft m.b.H. & Co KG (AT) | 1982-06-09 | — | — | EP | disclosed |